Treehouse of Horror X
As Springfield prepares for the ball drop for the new millennium, Homer boastfully claims that he fixed all of the nuclear power plant's computers in anticipation of Y2K; however he forgot to take care of his own, which allows a virus to spread across the globe.
Technology runs rampant (street lights shooting lasers, waffle irons attacking the family, etc.) and the Simpsons discover that there is a contingency to remove all important personnel off-world and Lisa is on the list. She, Maggie and Marge board the rocket, leaving Homer and Bart behind. The two then discover an unguarded rocket that they quickly board, and it launches just before the Earth begins to explode.
They then survey their fellow passengers, and notice they are in the midst of many obnoxious B-list celebrities: Rosie O'Donnell, Pauly Shore, Tom Arnold, and the like. Homer then realizes their ship is heading straight for the sun, and rather than endure five minutes with the others, he and Bart jettison themselves out of the rocket.
Best Quote (Matt): Guard: Now Lisa, you can only take one parent with you, so I'll give you some time to-
Lisa: (unflinchingly) Mom.
Best Quote (Josh):
Lisa: Well, look at the wonders of the computer age now.
Homer: Wonders, Lisa or blunders?
Lisa: I think that was implied by what I said.
Homer: Implied, Lisa or implode?
Lisa: Mom, make him stop.
Best Scene (Both): Homer and Bart willingly ejecting themselves from a spaceship filled with B-list celebrities before it actually reaches the Sun so as not to hang around them for 5 more minutes.